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University · University of Chicago

University of Chicago

A research powerhouse with an unusually structured venture programme through the Polsky Center and Booth's New Venture Challenge.

Location
Chicago, Illinois
Tier
Top 20 US
Known For
Fintech, Quantum, Enterprise

Overview

The University of Chicago is known for rigorous economics, physical sciences, and its business school, Booth. It manages Argonne and Fermi national laboratories, giving it access to research infrastructure few universities can match.

That combination produces founders at both ends: quantitative finance and enterprise software on one side, deep physical science on the other.

Startup Ecosystem

The Polsky Center for Entrepreneurship and Innovation coordinates venture activity, and Booth's New Venture Challenge is one of the longest-running and most successful university startup competitions in the country.

Duality, a quantum-focused accelerator run with Argonne, reflects the university's unusual access to national laboratory research.

Accelerators & Programs

  • Polsky Center for Entrepreneurship and Innovation
  • New Venture Challenge at Chicago Booth
  • Duality — quantum technology accelerator with Argonne
  • Polsky Exchange — incubator and co-working space
  • George Shultz Innovation Fund

Founder Output

Grubhub emerged from the New Venture Challenge, co-founded by a Chicago Booth student. The university's broader output spans fintech and trading technology, enterprise software, and increasingly quantum and materials science ventures from its national laboratory connections.

Local Investors

Chicago's investor base includes Hyde Park Venture Partners, Chicago Ventures, and Pritzker Group Venture Capital, alongside the trading and quantitative finance community that provides both capital and technical talent.

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